Latent Space Transcripts

The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI

Inside the Model Factory — Eiso Kant, Poolside AI

🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences

Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO

🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI

Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks

Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan

The Professor of Outputmaxxing — Anjney Midha, AMP

🔬 The Self-Driving Lab — Joseph Krause, Radical AI

Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

🔬Scaling Past Informal AI - Carina Hong, Axiom Math

⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

GitHub's plan for Agents — Kyle Daigle, GitHub

Why Video Agent models are next — Ethan He, xAI Grok Imagine

The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray

🔬ESMFold2: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

Giving Agents Computers — Ivan Burazin, Daytona

Railway: The Agent-Native Cloud — Jake Cooper

The Next War Is Already Here. The West Isn't Ready. — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion

AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge

🔬Doing Vibe Physics — Alex Lupsasca, OpenAI

Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition

AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)

Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO

🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik

Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion

Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony

Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"

Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun

Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample

Dreamer: the Personal Agent OS — David Singleton

Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer

NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)

Cursor's Third Era: Cloud Agents

Every Agent Needs a Box — Aaron Levie, Box

METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity

[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka

🔬Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI

Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis

⚡️The End of SWE-Bench Verified — Mia Glaese & Olivia Watkins, OpenAI Frontier Evals & Human Data

Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin Casado & Sarah Wang of a16z

Owning the AI Pareto Frontier — Jeff Dean

🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery

The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI

🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White

🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White

Captaining IMO Gold, Deep Think, On-Policy RL, Feeling the AGI in Singapore — Yi Tay

Captaining IMO Gold, Deep Think, On-Policy RL, Feeling the AGI in Singapore — Yi Tay 2

Brex’s AI Hail Mary — With CTO James Reggio

Brex’s AI Hail Mary — With CTO James Reggio

Artificial Analysis: The Independent LLM Analysis House — with George Cameron and Micah-Hill Smith

Artificial Analysis: Independent LLM Evals as a Service — with George Cameron and Micah-Hill Smith

[State of Evals] LMArena's $1.7B Vision — Anastasios Angelopoulos, LMArena

[NeurIPS Best Paper] 1000 Layer Networks for Self-Supervised RL — Kevin Wang et al, Princeton

[NeurIPS Best Paper] 1000 Layer Networks for Self-Supervised RL — Kevin Wang et al, Princeton

[State of Code Evals] After SWE-bench, Code Clash & SOTA Coding Benchmarks recap — John Yang

[State of Evals] LMArena's $100M Vision — Anastasios Angelopoulos, LMArena

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

[State of RL/Reasoning] IMO/IOI Gold, OpenAI o3/GPT-5, and Cursor Composer — Ashvin Nair, Cursor

[State of RL/Reasoning] IMO/IOI Gold, OpenAI o3/GPT-5, and Cursor Composer — Ashvin Nair, Cursor

[State of AI Startups] Memory/Learning, RL Envs & DBT-Fivetran — Sarah Catanzaro, Amplify

[Latent Space LIVE @ NeurIPS] State of AI Startups 2025 — with Sarah Catanzaro, Amplify Partners

One Year of MCP — with David Soria Parra and AAIF leads from OpenAI, Goose, Linux Foundation

Steve Yegge's Vibe Coding Manifesto: Why Claude Code Isn't It & What Comes After the IDE

⚡️GPT5-Codex-Max: Training Agents with Personality, Tools & Trust — Brian Fioca + Bill Chen, OpenAI

SF Compute: Commoditizing Compute to solve the GPU Bubble forever

The Creators of Model Context Protocol

Unsupervised Learning x Latent Space Crossover Special

The Agent Network — Dharmesh Shah

Building Snipd: The AI Podcast App for Learning

⚡️The new OpenAI Agents Platform

⚡️How Claude 3.7 Plays Pokémon

Open Operator, Serverless Browsers and the Future of Computer-Using Agents

The Inventors of Deep Research