Josh Duhamel On Fame, Hormones, Fatherhood, Longevity, & Finding His Way Back

What It Covers

Actor Josh Duhamel discusses building Gatlin, a men's health platform launched in 2024, alongside his path from North Dakota to Hollywood fame. He covers testosterone replacement therapy, peptide protocols, fatherhood, relocating away from Los Angeles, and why he stopped treating hormone optimization as something to hide.

Key Questions Answered

• •Testosterone delivery method: Duhamel uses Kyzatrex, an oral testosterone pill taken twice daily that bypasses the liver and maintains stable hormone levels throughout the week. Unlike weekly injections, which cause levels to spike then gradually drop, this method keeps levels consistently elevated, making it a practical alternative for men who prefer avoiding needles.
• •Wolverine peptide stack: Gatlin offers a single daily injection combining four peptides — BPC-157, TB-500, KPV, and GHK-Cu — targeting joint repair, injury recovery, skin regeneration, and hair health. Duhamel reports accelerated healing comparable to what professional athletes now experience, with recovery timelines roughly half what they were a decade ago.
• •Gatlin onboarding process: New users answer intake questions on the site, receive a blood test kit by mail, return the sample, then consult via telemedicine with one of 15 licensed doctors or nurse practitioners. The baseline blood panel determines which protocol fits the individual, covering testosterone, peptides, NAD, and GLP-1 options.
• •NAD supplementation method: Duhamel self-administers NAD via insulin needle rather than IV infusion, citing convenience. He reports benefits including improved skin quality, hair health, and cellular regeneration. NAD is positioned within Gatlin's stack as a longevity-focused compound suitable for both men and women, distinct from the hormone and peptide protocols.
• •Muscle retention as a non-negotiable: Duhamel emphasizes that GLP-1 users must combine weight training with their protocol to avoid losing lean muscle alongside fat. He cites ipamorelin and tesamorelin, a synthetic HGH-stimulating peptide compound, as his primary tool for preserving muscle mass after 50, when natural retention becomes progressively harder without intervention.