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Protein, increasing bone mineral density, saturated fat and more reflections | Drew Harrisberg

136 min episode · 2 min read
·
Drew Harrisberg

Episode

136 min

Read time

2 min

Topics

Health & Wellness, Leadership, Philosophy & Wisdom

AI-Generated Summary

Key Takeaways

  • Bone density and exercise: The LIFTMOR trial showed postmenopausal women aged 58 plus increased bone mineral density zero to 2.9 percent on average through high-intensity resistance training, with some individuals gaining up to twelve percent at specific sites like the femoral neck, contradicting claims that exercise cannot increase bone mass after age sixty-five.
  • Plant protein requirements: Controlled studies show elderly subjects consuming 1.2 grams protein per kilogram bodyweight achieve equivalent muscle protein synthesis on vegan versus omnivorous diets. However, free-living studies reveal vegans struggle to reach this threshold, often consuming only 0.8 to 0.9 grams per kilogram, requiring intentional meal planning and protein supplementation.
  • Saturated fat and insulin resistance: While saturated fat independently increases ectopic fat accumulation more than polyunsaturated fat, total calorie surplus remains the primary driver of liver and pancreatic fat in type two diabetes. The magnitude of effect from excess calories substantially outweighs the impact of fat type, making weight management the critical intervention priority.
  • Resistance training benefits beyond bone: Five by five protocols at eighty-five percent one rep max improve functional outcomes including sit-to-stand performance, reaction time, vertical jump, and balance coordination. These adaptations reduce fall risk independent of bone mineral density changes, addressing the actual outcome elderly populations care about: avoiding fractures through preventing falls.
  • Ultra-processed food nuance: Not all ultra-processed foods carry equal health risks. Protein-fortified plant milks and high-quality protein powders classified as ultra-processed can strategically support adequate protein intake for older adults with reduced appetite, particularly when whole food consumption alone falls short of 1.2 grams per kilogram targets necessary for muscle preservation.

What It Covers

Drew Harrisberg and Simon Hill reflect on evolving views about protein intake, bone mineral density, saturated fat, and insulin resistance. They examine how controlled studies differ from real-world outcomes and discuss practical strategies for aging populations on plant-based diets.

Key Questions Answered

  • Bone density and exercise: The LIFTMOR trial showed postmenopausal women aged 58 plus increased bone mineral density zero to 2.9 percent on average through high-intensity resistance training, with some individuals gaining up to twelve percent at specific sites like the femoral neck, contradicting claims that exercise cannot increase bone mass after age sixty-five.
  • Plant protein requirements: Controlled studies show elderly subjects consuming 1.2 grams protein per kilogram bodyweight achieve equivalent muscle protein synthesis on vegan versus omnivorous diets. However, free-living studies reveal vegans struggle to reach this threshold, often consuming only 0.8 to 0.9 grams per kilogram, requiring intentional meal planning and protein supplementation.
  • Saturated fat and insulin resistance: While saturated fat independently increases ectopic fat accumulation more than polyunsaturated fat, total calorie surplus remains the primary driver of liver and pancreatic fat in type two diabetes. The magnitude of effect from excess calories substantially outweighs the impact of fat type, making weight management the critical intervention priority.
  • Resistance training benefits beyond bone: Five by five protocols at eighty-five percent one rep max improve functional outcomes including sit-to-stand performance, reaction time, vertical jump, and balance coordination. These adaptations reduce fall risk independent of bone mineral density changes, addressing the actual outcome elderly populations care about: avoiding fractures through preventing falls.
  • Ultra-processed food nuance: Not all ultra-processed foods carry equal health risks. Protein-fortified plant milks and high-quality protein powders classified as ultra-processed can strategically support adequate protein intake for older adults with reduced appetite, particularly when whole food consumption alone falls short of 1.2 grams per kilogram targets necessary for muscle preservation.

Notable Moment

Van Loon's unpublished research reveals that when elderly subjects shop and prepare their own meals rather than receiving controlled feeding, those following plant-based diets consume fewer total calories, lose weight, and fail to meet protein targets compared to omnivorous eaters, highlighting the critical gap between what controlled studies show is possible versus probable real-world outcomes.

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Episode Transcript

Welcome back to The Proof, and welcome to episode 400, a milestone that I am still having trouble believing. I started this show back in 2018 in Venice, Los Angeles, where I am right now, thinking at the time that I was late on the podcast scene. In reality, it was still early days. And since then, the show has been listened to more than 50,000,000 times with over 17,000,000 views on YouTube since mid twenty twenty two. We're certainly not the biggest podcast in the world, but truth be told, I never imagined that I'd be able to platform legitimate scientists, people like my dad, and reach this many people. So it is a milestone. It is something that I am really proud of, and I'm incredibly grateful to all of you for being a key part of that journey. Today's conversation with Drew Harrisburg, one of my best friends in the entire world, was recorded just a week before the Bondi terrorist attack, an event that really deeply shook the community that I lived in for the better part of a decade and a place that I was staying in the days leading up to it. In fact, I'd been walking that bridge and through the park every day the week before the event unfolded. And this is an area where Drew trains often. Many of my friends train in this area. And so this whole tragedy has really rocked so many people that we love. My heart goes out to all of the victims and their families. I'm not here to make political statements, but I do want to just say this. I love my Jewish friends, and I love my Muslim friends. And I'm of the belief that kindhearted, good spirited humans, Muslims, Jewish, or other, deserve to feel safe. In the shadow of something so heartbreaking, talking about protein and performance can feel almost trivial. But this conversation that you're about to hear with Drew also touches on something far deeper, what really matters in life and how fragile and precious it all is. It feels like a fitting conversation for episode 400. Please enjoy. Thanks for coming back. Been a while. Yeah. It's good to be back. In fact, I dug through the archives. My first time on the show was episode 62. And we're at 400 now. Pretty crazy. I don't know how many there's been in between them, but it feels like a lot. Well, 338. Of me. Of me on this day. But, yes, you're very good at math. Yeah. We know You're a very popular you're a popular guest, and and people have been messaging me almost every week to get you back on for whatever reason. I don't know why, but I'll take it. Here we are. And we thought that we could essentially, unscripted, just go through reflections. So people people will be listening to this episode, I think, 2026. I think what will be instructive for the …

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  • The LIFTMOR trial showed postmenopausal women aged 58 plus increased bone mineral density zero to 2.9 percent on average through high-intensity resistance training, with some individuals gaining up to twelve percent at specific sites like the femoral neck.

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