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Machine Learning Street Talk

When AI Discovers The Next Transformer - Robert Lange (Sakana)

78 min episode · 3 min read
·
Robert Lange

Episode

78 min

Read time

3 min

Topics

Productivity, Investing, Fundraising & VC

AI-Generated Summary

Key Takeaways

  • Sample Efficiency via Model Ensembling: Shinka Evolve reduces LLM query costs by running multiple frontier models (GPT, Gemini, Grok) simultaneously and using a Upper Confidence Bound bandit algorithm to adaptively route each program mutation to the best-performing model. This approach achieves competitive circle packing results in fewer than 200 evaluations, compared to the thousands typically required by similar systems like AlphaEvolve.
  • The "Problem-Problem" Bottleneck: Current evolutionary LLM systems treat the problem as fixed, but breakthroughs often require first inventing a surrogate or reformulated problem. Shinka Evolve demonstrated this when using a slightly relaxed circle-overlap constraint as a proxy problem accelerated convergence. Building systems that automatically generate and evolve problem formulations alongside solutions represents the next critical frontier for AI-driven discovery.
  • Stepping Stones Over Direct Optimization: Drawing from Kenneth Stanley's open-endedness research, Lange argues that starting from an impoverished or minimal initial solution generates more diversity and ultimately better results than starting from a highly optimized one. Systems that accumulate diverse intermediate solutions — even seemingly unproductive ones — build the combinatorial foundation needed for genuine breakthroughs, mirroring how biological evolution produces complexity through non-directed exploration.
  • Crossover and Full-Rewrite Mutations Add Diversity: Beyond diff-based patches used in AlphaEvolve, Shinka Evolve introduces two additional mutation operators: complete program rewrites and crossover between two parent programs. Sampling two parent programs and prompting the LLM to produce a complementary improvement proved especially useful on structured problems. A global "meta scratch pad" summarizes discoveries across the program tree and injects shared insights into subsequent system prompts.
  • AI Scientist v2 Implements Falsificationist Loop: Unlike v1's linear template-based execution, AI Scientist v2 runs a parallelizable agentic tree search where the LLM drafts its own experimental setup, executes code, receives numerical feedback, and iteratively refines hypotheses — mirroring Karl Popper's falsificationism. A workshop-level paper produced by the system passed the acceptance threshold at an ICLR workshop, marking the first fully autonomous compute-to-scientific-output pipeline.

What It Covers

Robert Lange from Sakana AI discusses Shinka Evolve, an open-source evolutionary framework that uses multiple LLMs in parallel to discover novel algorithms and scientific solutions. The system improves on AlphaEvolve's approach through model ensembling, UCB-based adaptive model selection, and crossover mutations, achieving state-of-the-art circle packing results in under 200 LLM evaluations.

Key Questions Answered

  • Sample Efficiency via Model Ensembling: Shinka Evolve reduces LLM query costs by running multiple frontier models (GPT, Gemini, Grok) simultaneously and using a Upper Confidence Bound bandit algorithm to adaptively route each program mutation to the best-performing model. This approach achieves competitive circle packing results in fewer than 200 evaluations, compared to the thousands typically required by similar systems like AlphaEvolve.
  • The "Problem-Problem" Bottleneck: Current evolutionary LLM systems treat the problem as fixed, but breakthroughs often require first inventing a surrogate or reformulated problem. Shinka Evolve demonstrated this when using a slightly relaxed circle-overlap constraint as a proxy problem accelerated convergence. Building systems that automatically generate and evolve problem formulations alongside solutions represents the next critical frontier for AI-driven discovery.
  • Stepping Stones Over Direct Optimization: Drawing from Kenneth Stanley's open-endedness research, Lange argues that starting from an impoverished or minimal initial solution generates more diversity and ultimately better results than starting from a highly optimized one. Systems that accumulate diverse intermediate solutions — even seemingly unproductive ones — build the combinatorial foundation needed for genuine breakthroughs, mirroring how biological evolution produces complexity through non-directed exploration.
  • Crossover and Full-Rewrite Mutations Add Diversity: Beyond diff-based patches used in AlphaEvolve, Shinka Evolve introduces two additional mutation operators: complete program rewrites and crossover between two parent programs. Sampling two parent programs and prompting the LLM to produce a complementary improvement proved especially useful on structured problems. A global "meta scratch pad" summarizes discoveries across the program tree and injects shared insights into subsequent system prompts.
  • AI Scientist v2 Implements Falsificationist Loop: Unlike v1's linear template-based execution, AI Scientist v2 runs a parallelizable agentic tree search where the LLM drafts its own experimental setup, executes code, receives numerical feedback, and iteratively refines hypotheses — mirroring Karl Popper's falsificationism. A workshop-level paper produced by the system passed the acceptance threshold at an ICLR workshop, marking the first fully autonomous compute-to-scientific-output pipeline.
  • Verification Remains the Hard Constraint: Generating candidate solutions is computationally easier than rigorously verifying them. LLMs can perform soft verification by latently tracing code execution, but this remains inexact and susceptible to reward hacking. Lange identifies automatic verifier design — systems that both formulate problems and construct their own correctness checkers — as the most critical unsolved challenge before AI-driven science can operate reliably without human oversight.

Notable Moment

Lange describes running Shinka Evolve with a slightly relaxed circle-overlap constraint as a proxy problem, which accelerated convergence. When the system was rerun with exact constraints, it took noticeably longer to reach the same solution quality — demonstrating that surrogate problem design, typically a human insight, could itself become an automated discovery target.

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Episode Transcript

I think a lot of sort of analogies from evolution transfer to scientific research, right, in the sense that we traverse a tree of different ideas or different experiments, and then in the paper, we report one path through that tree. When we run LLMs autonomously Yeah. They they tend to just kind of like, nothing interesting happens. But oftentimes, innovation for a specific problem might require first inventing a different problem. Right? Sort of automatically coming up with this reduction or, like, this, let's say, recursive nature of problem solving is something these systems right now not necessarily have built in intrinsically. Right? Oftentimes, it's easier to generate a lot of solutions than to actually, like, hard verify them. Right? The reason why I'm not that worried yet about labor market disruption is I still believe deeply that humans are the source of deep understanding and creativity in the world. If I didn't believe that, I would be very worried. So I think it's gonna be an amplifier of sort of these these latent dimensions humans are great at. Right? And I think one of the Rubicon moments is when the the new transformers architecture or something massive is discovered by AI, and we're all using it. NVIDIA GTC starts Monday in San Jose, and it's free to attend virtually online. There's already been a leak this week of something called Nemo Claw, which is an open source agent platform. And if it's real, it could be one of the bigger announcements this year. So it's definitely worth watching Jensen's keynote for that alone. I'm giving away a DGX Spark. NVIDIA just hikes the price $700. You probably heard about these memory shortages. Right? So, yeah, it's now $4,700, which is very, very expensive. And, Merv from Hugging Face, by the way, she got one for her birthday, and she said she literally cried. So it's a really cool bit of kit. If you register through my link in the description and you attend at least one session, then you are in the draw. This is a massive conference. Physical AI and robotics are gonna be the breakout theme, and Jensen does the keynote Monday at 11AM Pacific. The link is in the description. Don't miss it. Robert Landry, it's amazing to have you on MLS team. Thank you, Tim. It's a pleasure to be back. So you're working for Sukana? Tell us about that. Sukana AI is a Japanese, AI startup working mostly on, yeah, AI for Japan, and at the same time, sort of exploring exploring, let's say, novel or ambitious ideas on the research side. It's been around for over a year now. You're on you're one of the founding researchers. Right? Exactly. So Sukana has been around for now, like, almost two years, like, one and three quarters, I would say. And, yeah, it's pretty fascinating to to look back and, to look at the early days and how much the company sort of organizationally …

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  • by Sakana AI

    Robert Lange from Sakana AI discusses Shinka Evolve, an open-source evolutionary framework that uses multiple LLMs in parallel to discover novel algorithms and scientific solutions.
  • by Sakana AI

    AI Scientist v2 runs a parallelizable agentic tree search where the LLM drafts its own experimental setup, executes code, receives numerical feedback, and iteratively refines hypotheses — mirroring Karl Popper's falsificationism.
  • The system improves on AlphaEvolve's approach through model ensembling, UCB-based adaptive model selection, and crossover mutations, achieving state-of-the-art circle packing results in under 200 LLM evaluations.

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