Biohub: The Future of Biology is Open-Source with Co-Founders Mark Zuckerberg, Priscilla Chan, and Head of Science Alex Rives

Just wanna give tools to the whole scientific community. We wanna understand how biology works. I wanna understand the genetics of this person. I wanna understand the risks they have to different illnesses. My goal is to be able to treat the individual as an individual, understand the mechanisms, and be able to intervene. We'll have a bigger impact by getting this in more scientists' hands quicker by doing it as open source projects instead. It's not just like there's some factory somewhere that you can pay to produce the data. You actually need to invent new novel scientific approaches. The theory isn't that we're gonna cure the diseases. We're not. It's that we wanna help accelerate the pace of progress for the whole scientific field. We folded over 1,100,000,000 proteins and predicted their structures and we didn't design a model for antibodies. We didn't design a model to be able to bind one particular target. We just designed a model that could understand proteins. If we could design a protein to actually change the physiology, then we can actually cure someone. Today on No Priors, we're joined by Mark Zuckerberg, Priscilla Chan, and Alex Reeves. We'll be talking about Biohub and all their various efforts to now start applying AI at scale to do world models of cells and different levels of interactions across biology. Mark, Priscilla, thank you for doing this. Yeah. Thanks for having us. Fun. Alex, congratulations on new missions. Thank you. You guys made Biohub your primary philanthropic effort and then committed $500,000,000 to this virtual biology initiative. Can you tell us a little bit about, you know, why do that, and how did you go from we should fund this to this is, like, who we are? So Biohub, in its current form, we're super excited about. We feel like it's a really good fit for who we are and what we bring to the table and what we can achieve together. But this work started ten years ago when we were thinking about how can we give back. And Mark had Mark wanted to build an organization that could cure, prevent, and manage all disease by the end of the century. And we had a series of hilarious meetings with scientists that, like, famous Nobel Prize winning scientists were just laughing at us. Is that was that your starting line? We're just gonna cure all disease. No. No. And to be clear, we don't think that we're gonna be the ones curing the diseases. Our our goal is always to build tools that could accelerate the whole scientific field. That way, the scientific field collectively could cure all the diseases. But still But still people laughed at us. By the end of the century, it was a stretch. Now I think it's, like, too conservative. And so we kept being, like, okay, well, we had these series of funny, awkward educational conversations where we're, like, okay, but, like, why? Like, why do you …