This week, the a16z Podcast examined how AI is reshaping foundational tools and industries—from developer infrastructure to pharmaceuticals to enterprise operations. Conversations with GitHub's Scott Chacon and discussions on AI adoption in business revealed a common thread: the need to rethink existing systems rather than simply bolt AI onto them. The week also featured perspectives on media, correctness in software, and what actually matters when technology meets real-world constraints.
Episodes This Week
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Other Weeks
This Week in a16z Podcast (Jun 8 - Jun 14, 2026)
3 episodes · Jun 8 – Jun 14
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6 episodes · Jun 1 – Jun 7
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5 episodes · May 25 – May 31
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5 episodes · May 18 – May 24
This Week in a16z Podcast (May 11 - May 17, 2026)
5 episodes · May 11 – May 17
This Week in a16z Podcast (May 4 - May 10, 2026)
5 episodes · May 4 – May 10
This Week in a16z Podcast (Apr 27 - May 3, 2026)
5 episodes · Apr 27 – May 3
This Week in a16z Podcast (Apr 13 - Apr 19, 2026)
6 episodes · Apr 13 – Apr 19
This Week in a16z Podcast (Apr 6 - Apr 12, 2026)
4 episodes · Apr 6 – Apr 12
This Week in a16z Podcast (Mar 30 - Apr 5, 2026)
5 episodes · Mar 30 – Apr 5
This Week in a16z Podcast (Mar 23 - Mar 29, 2026)
5 episodes · Mar 23 – Mar 29
