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This Week in Startups

Anthropic’s Mythos is a cyber-weapon, so you can’t have it | E2273

76 min episode · 3 min read
·
Rob May

Episode

76 min

Read time

3 min

Topics

Career Growth, Productivity, Relationships

AI-Generated Summary

Key Takeaways

  • Cyber Weapon Classification: Mythos achieves roughly 59% on SWE-Bench multimodal versus 27% for Claude OS 4.6, doubling coding benchmark performance. Its ability to chain three to five independent vulnerabilities into a single sophisticated exploit makes it functionally a cyber weapon. Founders and security teams should treat any AI model with comparable code capabilities as an offensive tool requiring strict access controls, not just a productivity aid.
  • Project Glasswing Defensive Window: Anthropic allocated a $100 million compute credit fund for partners including AWS, Azure, and NVIDIA to harden critical infrastructure before Mythos releases publicly. Polymarket currently prices only a 28% chance of public release by June 30. Startups dependent on legacy open-source libraries like FFMPEG or OpenBSD should prioritize security audits now, using this three-to-five month window before equivalent capability spreads.
  • SLM Cost Reduction Strategy: AT&T reduced AI infrastructure token costs by 90% by routing 90% of workloads to small language models and reserving frontier models for the remaining 10% of complex tasks. At 8 billion tokens per day, this saved hundreds of thousands of dollars daily. Founders running high-volume, repetitive AI tasks should audit their OpenAI or Anthropic spend and identify which tasks a sub-10 billion parameter model can handle adequately.
  • Distillation as Cost Arbitrage: Companies can train task-specific small language models by capturing frontier model input-output pairs as a training dataset, a process called distillation. If a task runs thousands of times daily, such as extracting stock symbols from industry reports, distilling a dedicated SLM can cut per-task inference costs by up to 90%. The break-even threshold is roughly when the same prompt-response pattern repeats at scale daily.
  • Startup Defensibility Scoring Framework: Three categories consistently produce low AI-replaceability scores: physical hardware products, genuine network effects where value scales with user count, and deeply regulated industries requiring human relationships. Software products functioning as AI wrappers around frontier models score highest for replaceability. Founders should stress-test their product by asking whether a 31-line Claude prompt could replicate their core function before raising or scaling.

What It Covers

Anthropic's unreleased model Claude Mythos can autonomously chain multiple software vulnerabilities into sophisticated exploits, discovering more zero-day security flaws than human researchers find in careers. The episode covers the national security implications, Project Glasswing's defensive deployment with major tech partners, and the parallel rise of small language models as a cost-cutting alternative to frontier AI spending.

Key Questions Answered

  • Cyber Weapon Classification: Mythos achieves roughly 59% on SWE-Bench multimodal versus 27% for Claude OS 4.6, doubling coding benchmark performance. Its ability to chain three to five independent vulnerabilities into a single sophisticated exploit makes it functionally a cyber weapon. Founders and security teams should treat any AI model with comparable code capabilities as an offensive tool requiring strict access controls, not just a productivity aid.
  • Project Glasswing Defensive Window: Anthropic allocated a $100 million compute credit fund for partners including AWS, Azure, and NVIDIA to harden critical infrastructure before Mythos releases publicly. Polymarket currently prices only a 28% chance of public release by June 30. Startups dependent on legacy open-source libraries like FFMPEG or OpenBSD should prioritize security audits now, using this three-to-five month window before equivalent capability spreads.
  • SLM Cost Reduction Strategy: AT&T reduced AI infrastructure token costs by 90% by routing 90% of workloads to small language models and reserving frontier models for the remaining 10% of complex tasks. At 8 billion tokens per day, this saved hundreds of thousands of dollars daily. Founders running high-volume, repetitive AI tasks should audit their OpenAI or Anthropic spend and identify which tasks a sub-10 billion parameter model can handle adequately.
  • Distillation as Cost Arbitrage: Companies can train task-specific small language models by capturing frontier model input-output pairs as a training dataset, a process called distillation. If a task runs thousands of times daily, such as extracting stock symbols from industry reports, distilling a dedicated SLM can cut per-task inference costs by up to 90%. The break-even threshold is roughly when the same prompt-response pattern repeats at scale daily.
  • Startup Defensibility Scoring Framework: Three categories consistently produce low AI-replaceability scores: physical hardware products, genuine network effects where value scales with user count, and deeply regulated industries requiring human relationships. Software products functioning as AI wrappers around frontier models score highest for replaceability. Founders should stress-test their product by asking whether a 31-line Claude prompt could replicate their core function before raising or scaling.
  • Harness Engineering for SLM Reliability: Small language models lose task focus on complex multi-step workflows, but wrapping them in structured harnesses that require the model to check back against the original objective at each step dramatically improves reliability. Claude Code can generate these harnesses for specific tasks. Teams using SLMs for agentic workflows should build explicit checkpoint logic into their orchestration layer rather than relying on the model's native instruction-following alone.

Notable Moment

During a live demo of the tool Death by Claude, guest Gianni revealed his own startup scored 92 out of 100 on replaceability, meaning the product he built to survive AI disruption was itself declared nearly dead by AI. The tool then generated a 31-line prompt to replace his entire company.

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Episode Transcript

Alright, everybody. Welcome to Twist. It's 04/08/2026. My cohost, Alex, is with me. We've got a bunch of guests today, and we've got a major breaking news story, which is that Anthropic released a promo video and a thread that their new model, Alex, is so powerful that they cannot release it. We knew this day would come. The day is here. Why can't they release it? They believe, when they tested it or they found out when they tested it that it would try to escape. That was one issue. But a bigger issue was it could find exploits in ten, twenty, thirty year old software projects that, and it could thread together multiple security vulnerabilities. Catch everybody up in the audience on this incredibly important story. This Week in Startups is brought to you by LinkedIn jobs. Hire right the first time. Post your job and get $100 off towards your job post at linkedin.com/twist. Grasshopper Bank. Time is money. Don't waste either. Go to grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account. And render. Find out why 5,000,000 developers are already using the all in one cloud platform render. Go to render.com/twist and apply for the render startup program to get 500 to $100,000 in free credits depending on your stage and backers. Big model race going on between the major AI labs. Anthropic is now very far out in front with its new model called Mythos. It is a general purpose LLM, so it's not tuned for one specific task. It is currently in preview. You cannot use it. A consortium of companies, Jason, are working with Anthropic to basically use it in a defensive capacity because as you said, Mythos is incredible at both finding, exploiting, and patching security vulnerabilities in software that humans have often missed. This goes back decades as you said to things like OpenBSD, a famously secure piece of software. It found something there. It found something in FFMPEG, which is an important part of the open source infrastructure of online video, for example. Basically, the gist is with this model, anyone can go to any piece of software and find zero day exploits quickly and then basically go to war with them. So Anthropic cannot let this out of the bag because if they did, then North Korea and China and everyone else could use it to essentially break the modern digital infrastructure that we depend on. So today, Jason, project Glasswing is the goal. Bunch of companies, your NVIDIA's, your AWS's, your Azure's are all gonna work with Anthropic to basically take the model Mythos preview and harden everything. Anthropic has also put together a $100,000,000 credit fund essentially saying, here, use the model up to a $100,000,000 of compute, to essentially harden these systems. So I think that Anthropic is doing the right thing here by saying, hey, we're not gonna release something this dangerous, you know, from this off the cuff, but …

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    During a live demo of the tool Death by Claude, guest Gianni revealed his own startup scored 92 out of 100 on replaceability

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