#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration

Hey, everyone. Welcome to a sneak peek, ask me anything or AMA episode of the Drive podcast. I'm your host, Peter Attia. At the end of this short episode, I'll explain how you can access the AMA episodes in full along with a ton of other membership benefits we've created. Or you can learn more now by going to peterattiamd.com forward slash subscribe. So without further delay, here's today's sneak peek of the Ask Me Anything episode. Welcome to Ask Me Anything AMA episode 84. In today's AMA, I answer listener questions across a wide range of topics, less about deep dives and more about how I think through real world trade offs and apply the science and practice. In today's episode, we're going to discuss how to build and analyze a meaningful family health history, how risk tolerance changes decisions around testing and treatment, why heart disease remains so poorly prevented despite the tools we already have, whether someone can carry excess body fat and still remain metabolically healthy, the minimum effective dose for strength training for people who don't have a lot of time, the habits and interventions that may matter most for reducing dementia risk, what would need to change for me to reconsider my point of view on the supplements that boost NAD, such as NR and NMN, and when hydration and electrolytes matter and when they're mostly overkill. So without further delay, I hope you enjoy AMA number 84. Peter, welcome to another AMA. Today's AMA gonna be another mixed bag of topics covering a variety of things. Again, these aren't meant to be deep dives on the science. The focus is more how you talk with patients, how you think about decisions, how you weigh trade offs for yourself and for others. And so we'll move across a variety of topics. This will include conversations around family history, what it is, when it's more useful than genetic testing, how you use it with patients and how people should think about it, how you think about various people's different feelings around taking risks as it relates to their health and how that affects their decision. Look at cardiovascular disease prevention, ideas around can someone be metabolically healthy while still being overweight and what that looks like. We'll talk about strength training. What is the potential minimum effective dose and how do you prioritize different exercises for people who are busy, which is the vast majority of people listening to this? We'll also look around dementia risk, any updated thoughts on NAD boosters such as NMN, NR, hydration, electrolytes, and more. So all that said, I think we'll get into it with talking about family history. So we've talked about family history before as something that you find very insightful and sometimes, if not often, even more insightful than genetic tests. So before we get into the best way for someone to collect and analyze their family history, do you wanna just kind of talk about …