Labiotech's 15 biopharma companies to watch in 2026
Episode
41 min
Read time
2 min
Topics
Investing, Fundraising & VC, Design & UX
AI-Generated Summary
Key Takeaways
- ✓Abivax maintenance data as inflection point: Abivax's oral microRNA therapy for ulcerative colitis drove a roughly fivefold stock increase after positive phase three induction data in 2025. The critical 2026 catalyst is maintenance data confirming durability of remission. Separately, M&A speculation involving Eli Lilly adds a second layer of investor attention worth monitoring alongside the clinical readout.
- ✓Radiopharma maturation signal: Radiopharma is transitioning from niche to platform, evidenced by big pharma entering the space and growing attention to isotope supply chains and manufacturing logistics — historically overlooked infrastructure. ITM (Isotope Technologies Munich) serves as a sector barometer, combining its own pipeline with isotope supply capabilities and multi-cycle experience in the European market.
- ✓GLP-1 competitive pressure on Novo Nordisk: Novo Nordisk faces structural pressure in 2026 from a lapsed GLP-1 patent in Canada opening generic competition, Pfizer acquiring a GLP-1 asset Novo bid on, and internal pipeline diversification via next-generation candidate Amicretin. Tracking Novo reveals how dominant GLP-1 franchises respond when market exclusivity erodes and competition intensifies simultaneously.
- ✓Psychedelic trial design as competitive differentiator: MindMed's MM-120 holds FDA breakthrough therapy designation and is in phase three trials for generalized anxiety disorder and major depressive disorder, with top-line anxiety results expected in the first half of 2026. Rigorous trial design — specifically addressing functional blinding issues that derailed Lykos Therapeutics' MDMA PTSD application — positions MindMed ahead of sector peers.
- ✓Chinese-licensed assets entering global trials: Both Kilera Therapeutics and Braveheart Bio licensed cardiovascular and metabolic candidates from Jiangsu Hengrui Pharmaceuticals. Kilera's GLP-1/GIP dual agonist showed 22.8% mean weight loss at 36 weeks in phase two at higher doses, with a $600M series B funding a global phase three program launching in 2026 — a replicable pipeline-building model worth tracking.
What It Covers
Three Labiotech journalists — Jules Adam, Willow Sharnival, and Rui Peter — each identify five biopharma companies to watch in 2026, spanning radiopharma, gene therapy, psychedelics, GLP-1 obesity drugs, and cardiovascular medicine, totaling 15 companies with near-term clinical catalysts.
Key Questions Answered
- •Abivax maintenance data as inflection point: Abivax's oral microRNA therapy for ulcerative colitis drove a roughly fivefold stock increase after positive phase three induction data in 2025. The critical 2026 catalyst is maintenance data confirming durability of remission. Separately, M&A speculation involving Eli Lilly adds a second layer of investor attention worth monitoring alongside the clinical readout.
- •Radiopharma maturation signal: Radiopharma is transitioning from niche to platform, evidenced by big pharma entering the space and growing attention to isotope supply chains and manufacturing logistics — historically overlooked infrastructure. ITM (Isotope Technologies Munich) serves as a sector barometer, combining its own pipeline with isotope supply capabilities and multi-cycle experience in the European market.
- •GLP-1 competitive pressure on Novo Nordisk: Novo Nordisk faces structural pressure in 2026 from a lapsed GLP-1 patent in Canada opening generic competition, Pfizer acquiring a GLP-1 asset Novo bid on, and internal pipeline diversification via next-generation candidate Amicretin. Tracking Novo reveals how dominant GLP-1 franchises respond when market exclusivity erodes and competition intensifies simultaneously.
- •Psychedelic trial design as competitive differentiator: MindMed's MM-120 holds FDA breakthrough therapy designation and is in phase three trials for generalized anxiety disorder and major depressive disorder, with top-line anxiety results expected in the first half of 2026. Rigorous trial design — specifically addressing functional blinding issues that derailed Lykos Therapeutics' MDMA PTSD application — positions MindMed ahead of sector peers.
- •Chinese-licensed assets entering global trials: Both Kilera Therapeutics and Braveheart Bio licensed cardiovascular and metabolic candidates from Jiangsu Hengrui Pharmaceuticals. Kilera's GLP-1/GIP dual agonist showed 22.8% mean weight loss at 36 weeks in phase two at higher doses, with a $600M series B funding a global phase three program launching in 2026 — a replicable pipeline-building model worth tracking.
Notable Moment
Kilera Therapeutics raised $400M at launch, then secured an additional $600M series B — totaling $1B — for a single GLP-1/GIP obesity asset licensed from a Chinese company. Investors committed this capital based largely on phase three data from Chinese trials, signaling a shift in how global biopharma evaluates non-Western clinical evidence.
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